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Official launch of Covid-Organics: improved traditional remedy with curative and preventive properties of coronavirus symptoms
Scientific studies by the Malagasy Institute for Applied Research (IMRA) against covi-19 have resulted in the development of an improved traditional remedy with curative and preventive properties of coronavirus symptoms. This is the Covid-Organics or Tambavy CVO composed of Artemisia and medicinal plants endemic to Madagascar. The President of the Republic, accompanied by his wife, officially launched the Covid-Organics on April 20, 2020 at the IMRA headquarters. Madagascar produces the greatest quantity and the best quality of Artemisia. This plant is already used in the fight against malaria and fever. Prof. Albert Rakoto Ratsimamanga, founder of IMRA, was the first to study it on the territory. According to the Director General of IMRA, Charles Andrianjara, the results of the first clinical trials of Covid-Organics on patients with the coronavirus are encouraging and demonstrate a trend in its curative efficacy. To the Director General of IMRA to add that therapeutic trials are currently continuing. The Covid-Organics, existing in the form of decoctions and herbal teas to be infused, will be distributed free of charge to the most vulnerable populations and put on the market (decoction of 33Cl at 1500 Ar, from 1L to 3000 Ar, the box of 14 pods at 10,000 Ar) from April 22, 2020. Production and research will be conducted by IMRA with the support of the Malagasy government. The President of the Republic also announced during the ceremony that all the profits from the sale of Covid-Organics will be donated to the IMRA in order to finance the development of Malagasy scientific research. Still according to the Head of State, the popularization of the consumption of Covid-Organics among all Malagasy people participates in the implementation of strategic measures applied by the State to fight against the coronavirus. "The imperative is to save the Malagasy population" declared President Andry Rajoelina.
In addition, he stressed that this is a first step and that research is continuing for the development of a more extensive curative treatment protocol. President Andry Rajoelina did not fail to thank and encourage the frontline agents in the fight against the coronavirus. Namely the teams of the medical profession, the police, the Malagasy scientific community as well as members of the government. To convince those who are reluctant and to remove the doubt, the Head of State and his wife, as well as the Prime Minister and members of the government present at IMRA publicly drank several sips of Tambavy CVO. The event was broadcast live on Malagasy Television.
Directorate of Communication and Public Relations
Albert and Suzanne Rakoto Ratsimamanga Foundation
Discussion
IMRA’s approach to drug development and commercialization was adapted from the outset to Malagasy culture and Southern economic landscapes. It achieved a balance between employing Northern R&D practices and following local cultural norms through four guiding principles. First, IMRA’s researchers understood and respected local practices, and sought to use rather than resist them. Second, IMRA engaged the local community early in the drug development process, and ensured that local people had a stake in its success. Third, IMRA actively collaborated with local and international partners to increase its credibility and research capacity. Fourth, IMRA obtained foreign research funds targeting the “diseases of civilization” to cross-fund the development of drugs for conditions that affect the Malagasy population. These principles are illustrated in the development of IMRA products like Madeglucyl, a treatment for diabetes management that was developed from a traditional remedy.
Summary
By combining local and international research interests, IMRA has been able to keep its treatments affordable for the Malagasy population. Our analysis of IMRA’s history, strategy, and challenges suggests that other developing world institutions seeking to use bioprospecting to address issues of local access to medicines would be well-advised to treat traditional medical knowledge with respect and humility, share its benefits with the local community, and pursue strategic partnerships.
Madagascar: biodiversity threatened by biopiracy
With over 5% of the world’s biodiversity on 0.004% of the world’s landmass, Madagascar is one of the world’s top three conservation hotspots [4–6]. The Malagasy people, however, are the seventh poorest people in the world. Madagascar’s political history, from French colonial rule in the 19th and 20th centuries to a military coup in 2001 and more recent political troubles, has only exacerbated the historic divides within its ethnically heterogeneous population [4, 5].
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